<!DOCTYPE html>
<html lang="en">
<head>
    <meta charset="UTF-8">
    <meta http-equiv="X-UA-Compatible" content="IE=edge">
    <meta name="viewport" content="width=device-width, initial-scale=1.0">
    <title>Document</title>
    <style>
    *{
        margin: 0;
        padding: 0;
    }

    .wrap{
        width: 100vw;

    }
    .header, .footer{
        width: 100vw;
        height: 50px;
        background-color: gray;
    }
    .content{
        width: 100vw;
        height: 200px;
        background-color: red;
    }
    .left ,.right{
            width: 200px;
            height: 200px;
            background-color:pink;
    }
    .left ,.right,.detail {
        float: left;
    }
    .left{
        margin-left: -100%;
    }
    .right{
        width: 300px;
        margin-left: -300px;
    }
    .detail{
        width: 100vw;
    }
    .detail-inner{
        margin: 0 200px;
    }
</style>
</head>
<body>
    <div class="wrap">
        <div class="header"></div>
        <div class="content">
            <div class="detail">
                <div class="detail-inner">
                    内容内容内容内容
                </div>
            </div>
            <div class="left">广告</div>
            
            <div class="right">广告</div>
        </div>
        <div class="footer"></div>
    </div>
</body>
</html>